Basic Information
VIS ID
TVIS44029490
Fusion event
HTLV-1-C1QBP integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
5281970/5437926 (Hg38)
End
5281970/5437926 (Hg38)
Orient
-
Location type
Intronic
Target gene
C1QBP
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-1274a ; hsa-mir-93-3p ; hsa-mir-484 ; hsa-mir-378a-5p ; hsa-mir-301a-3p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30a-3p ; hsa-mir-193b-3p ; hsa-mir-193a-3p
Nearest miRNA
hsa-mir-1253/Upstream/467776; hsa-mir-10226/Downstream/1217514;
Nearest TSS
ENST00000595228/Upstream/3816; ENST00000571506/Downstream/841;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/17530, chr17-CpG: 56/Downstream/979
Upstream sequence
ACATTAGAGAGCAGTGTCCTATTTTATCAGGGCTGTAAATCAGAGATCAAACTGATTCTGCCAGTACTTTTTTGCACTACATTTTTGTCTCCTTAGTAAC
Downstream sequence
CAGCCCACAGCAAATTTGTGTTCGGTGAATGGACTGCCTGGGGCTTACGAAGTTGTCCAAATGAATCCTTCACTCTCTTGAAACCCATTTATCAAAGTAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate