Basic Information
VIS ID
TVIS44029493
Fusion event
HTLV-1-CHP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
NCBI36/hg18
Start
39313682/41234192 (Hg38)
End
39313682/41234192 (Hg38)
Orient
+
Location type
Intronic
Target gene
CHP1
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-144-3p ; hsa-mir-3133 ; hsa-mir-4476 ; hsa-mir-4524b-3p ; hsa-mir-4781-3p ; hsa-mir-567 ; hsa-mir-6077 ; hsa-mir-6079 ; hsa-mir-6828-5p ; hsa-mir-6876-5p ; hsa-mir-7-5p ; hsa-mir-8065 ; hsa-mir-9500 ; hsa-mir-1273g-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-3612 ; hsa-mir-377-5p ; hsa-mir-4252 ; hsa-mir-4257 ; hsa-mir-4459 ; hsa-mir-455-3p ; hsa-mir-4695-5p ; hsa-mir-4793-3p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6807-5p ; hsa-mir-6840-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/4261291; hsa-mir-10393/Downstream/457393;
Nearest TSS
ENST00000557528/Upstream/2899; ENST00000560633/Downstream/22492;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/2658, chr15-CpG: 51/Downstream/49651
Upstream sequence
gcgcataccaccatgcttacctgatttttatttttatcttttgtagagatggagtcttgttattttgtcgaggctggtcataaactcctggcctcaagtg
Downstream sequence
attcttaggccacttcaacctcccaaagcacggggattacaggtgtgagccactgcgccaagccCAGAGTTGTTTTTTCAAGGAGTAATTTGGTATGATG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate