Basic Information
VIS ID
TVIS44029503
Fusion event
HTLV-1-ANKRD6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
NCBI36/hg18
Start
90387786/89621346 (Hg38)
End
90387786/89621346 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6G
Target gene
ANKRD6
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-653-5p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-1264
Nearest miRNA
hsa-mir-10398/Upstream/11082037; hsa-mir-1202/Downstream/691396;
Nearest TSS
ENST00000381078/Upstream/132; ENST00000521004/Downstream/520;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/187430, chr6-CpG: 40/Downstream/17102
Upstream sequence
aaatcacttgcccagagaccctatagccagtagctactgggttcaaactgagatctgttctgacccacctatgtttttctgtgtccattctgtcactctg
Downstream sequence
CACTGTAAGAGGCAGAGTAAATGCTTCCTTTTGGGGAAGAGATAACTGTCCCGTGGTTGGTACTATGGCTCATAGATACACTTTAATAATATTTTGAATC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate