Basic Information
VIS ID
TVIS44029504
Fusion event
HTLV-1-SEC24D integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
NCBI36/hg18
Start
119868420/118727817 (Hg38)
End
119868420/118727817 (Hg38)
Orient
-
Location type
Intronic
Target gene
SEC24D
miRNAs that regulate target gene
hsa-mir-605-5p ; hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-129-5p ; hsa-mir-511-5p ; hsa-mir-6830-3p ; hsa-mir-6878-3p ; hsa-mir-640 ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-378a-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-4312 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-4680-5p ; hsa-mir-4635 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-212-5p ; hsa-mir-6747-3p ; hsa-mir-6513-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-6131
Nearest miRNA
hsa-mir-12113/Upstream/4070963; hsa-mir-1305/Downstream/6779442;
Nearest TSS
ENST00000502981/Upstream/30606; ENST00000434046/Downstream/1030;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/42162, chr4-CpG: 56/Downstream/108224
Upstream sequence
CTTAAACTGAACCATAGGTGCTGTGTGGTGTGAAAACTGTTCTAGAAAAGTTGTGTATTCATCCAGATGTCATTAGTTCAATTTACCTAAGCTCTACCTA
Downstream sequence
AAGTTGATGTTTGCATGCATGAGTTACTTTCACAGTTACGAATGTTGGTTCAGATTGACATCACATTTACATTTCAGGAGACAACTGGCCCCATAAATAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate