Basic Information
VIS ID
TVIS44029506
Fusion event
HTLV-1-C18orf54 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
NCBI36/hg18
Start
50158403/54378035 (Hg38)
End
50158403/54378035 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA18B
Target gene
C18orf54
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-1-2/Upstream/1140845; hsa-mir-122/Downstream/1101186;
Nearest TSS
ENST00000575820/Upstream/3785; ENST00000585973/Downstream/209722;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/19411, chr18-CpG: 30/Downstream/450338
Upstream sequence
AATGTCAAAAAATATAATTTTTAAAGTAAATGTTTATAGAACTTTAGATAAATTATTTTAACCCTCAATTATTCAGATCTCAAGGTTTTATAAGGAATAA
Downstream sequence
GTCTCAAAGTTTATATAAATTTACTTCTCATACCAATTTTGAAGTTAATAGTCAACTTTATTTATTTTTTTGCTGTCTGCATTGGCTATTCAGTTCTTAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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