Basic Information
VIS ID
TVIS44029511
Fusion event
HTLV-1-KCTD16 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q31.3
Reference genome
NCBI36/hg18
Start
143656366/144296610 (Hg38)
End
143656366/144296610 (Hg38)
Orient
-
Location type
Intronic
Target gene
KCTD16
miRNAs that regulate target gene
hsa-mir-3124-3p ; hsa-mir-6837-3p ; hsa-mir-3121-5p ; hsa-mir-205-5p ; hsa-mir-377-3p ; hsa-mir-342-3p ; hsa-mir-483-3p ; hsa-mir-4643 ; hsa-mir-603 ; hsa-mir-129-5p ; hsa-mir-33a-5p ; hsa-mir-33b-5p ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-4729 ; hsa-mir-507 ; hsa-mir-557
Nearest miRNA
hsa-mir-10397/Upstream/616639; hsa-mir-103a-1/Downstream/4765703;
Nearest TSS
ENST00000502646/Upstream/91333; ENST00000512571/Downstream/932372;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/91109, chr5-CpG: 20/Downstream/302056
Upstream sequence
TCTATAGATATAATAAAATAATCAAATCTTAAAACTGTGTCTATGCTATAGGGATCCTTTTAAAAAATTCAACAATTATTTGGAGAACTTCACTGTATTC
Downstream sequence
TAAGTGCCTGAGTTGTAAACTACTGTAACTAGCTAGAGAATTCGTCATCCTCTGGAGCATTTGGGTGCTTAGCAGAAAAACAAAAGAAAACTACTAGATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate