Basic Information
VIS ID
TVIS44029543
Fusion event
HTLV-1-EBF3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
NCBI36/hg18
Start
131590329/129902075 (Hg38)
End
131590329/129902075 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
EBF3
Nearest miRNA
hsa-mir-107/Upstream/58701; hsa-mir-202/Downstream/1060513;
Nearest TSS
ENST00000439456/Upstream/56747; ENST00000486974/Downstream/61766;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2927, chr10-CpG: 179/Downstream/56351
Nearest cancer related gene
EBF3(TSG, No orient, 0)
Upstream sequence
CCTGTAAAACCTTTCCCCATGATAAATAAATGCAAACTCTGCTTCCTATTAGCTGAGGTGATGCTTTTAATACAAAATCTACAGCCTGTGCCTACTAGGG
Downstream sequence
GAGCAACATGTTAACTTCTGCAACTGGGGAAGTTTTCGGGGAATTAGAAGTGAGTTTACTTCATCTAGCGCCACACTTAGTTCCCCACCACAACGCAGCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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