Basic Information
VIS ID
TVIS44029551
Fusion event
HTLV-1-CELF5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
NCBI36/hg18
Start
3219742/3268744 (Hg38)
End
3219742/3268744 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
CELF5
miRNAs that regulate target gene
hsa-mir-3144-5p ; hsa-mir-3925-3p ; hsa-mir-515-5p ; hsa-mir-519e-5p ; hsa-mir-629-3p ; hsa-mir-766-3p
Nearest miRNA
hsa-mir-1227/Upstream/637951; hsa-let-7e/Downstream/692670;
Nearest TSS
ENST00000633603/Upstream/43259; ENST00000589370/Downstream/1870;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/39750, chr19-CpG: 45/Downstream/1737
Upstream sequence
GGGCTAAGGGTCTTGGTGGGGAACGGAGGGTCACAAAGCCCAGTGCCCTTGTGCCCCTGCCTCCCACCGGAGCTACCCCAAGTGAGGGGCAGTGTGTGTG
Downstream sequence
TTTAGTGGGGAGGGGTCGTAATCAAGGTAATGCCTGGGCAAGACAATGGAAGCAGATGGAGAGAGAGCACGGAAGACTTCAGGGAGGAGGTGGCGTTTGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate