Basic Information
VIS ID
TVIS44029565
Fusion event
HTLV-1-GAD1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
171396821/170832065 (Hg38)
End
171396821/170832065 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
GAD1
Nearest miRNA
hsa-mir-128-1/Upstream/2249047; hsa-mir-10b/Downstream/4335568;
Nearest TSS
ENST00000437798/Upstream/3097; ENST00000462739/Downstream/11737;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/8217, chr2-CpG: 92/Downstream/96899
Upstream sequence
aaaaaaaagaaTTTTCATTCTTGGATTTAGGCTATTCACAACCTAAAGAGAGCAGAATGACCCATCCTCTGCTTCTTTTCTTGCCTCCATTTTCAGGTCT
Downstream sequence
ATTTCATTCTGATAAATCCTGCCCTTGCCTGTCCCTGACACTGGGGAGAATTGGGCTATTTCCTCTCCCTTTCtgtattagtttcctaggaatgccatta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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