Basic Information
VIS ID
TVIS44029586
Fusion event
HTLV-1-GALNT2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
NCBI36/hg18
Start
228480885/230278516 (Hg38)
End
228480885/230278516 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
GALNT2
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-1226-3p ; hsa-mir-99b-3p ; hsa-mir-7855-5p ; hsa-mir-6515-5p ; hsa-mir-4443 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-1909-5p ; hsa-mir-432-5p ; hsa-mir-5690 ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-6813-3p ; hsa-mir-3200-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1816364; hsa-mir-1182/Downstream/741312;
Nearest TSS
ENST00000473358/Upstream/10033; ENST00000633012/Downstream/3377;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/210054, chr1-CpG: 24/Downstream/1080
Upstream sequence
CACTCAGGCTGAAAGGGGTATTTATGTTACTTGCTAAACAGGGCTCCTCAGATTTCCTTCAGGCTGGGTTGTGCACTTTGATTCTGGCTTAGTTGGTGGG
Downstream sequence
TAACGGGTATGTGGGTTGAGTTTGGTTGTTCGCTTGATTTGAGTGTTAGTAAAGAGGCATCGTACCCTGTACTTTACAAGCGGCATGTTCAGAACTCAGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate