Basic Information
VIS ID
TVIS44029592
Fusion event
HTLV-1-NTPCR integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
NCBI36/hg18
Start
231167085/232964716 (Hg38)
End
231167085/232964716 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
NTPCR
miRNAs that regulate target gene
hsa-mir-92a-3p ; hsa-mir-3674 ; hsa-mir-135b-3p ; hsa-mir-7977 ; hsa-mir-6806-5p ; hsa-mir-383-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-564
Nearest miRNA
hsa-mir-101-1/Upstream/1944792; hsa-mir-1537/Downstream/659436;
Nearest TSS
ENST00000473358/Upstream/2813; ENST00000366623/Downstream/20836;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/13867, chr1-CpG: 18/Downstream/21465
Upstream sequence
GCAGTAATTAACAAACATAAAATTACTATACATTGAAGCTGCACTAAAAAAAATGCCATAATGGTTAAGCTTTTTTCCACTCTAAGCTGTGCTTCTCTCT
Downstream sequence
ATTTGTATCCGGTTACCTCCCCATTAGAAAAGCCATCACCATTTTATTATAGGAAAAACAATCAGTTCTTTCTCCTCAGGCAGTTTCTAATGAAAACGGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate