Basic Information
VIS ID
TVIS44029603
Fusion event
HTLV-1-C1RL integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
NCBI36/hg18
Start
7147593/7103721 (Hg38)
End
7147593/7103721 (Hg38)
Orient
+
Location type
Intronic
Target gene
C1RL
miRNAs that regulate target gene
hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-4710 ; hsa-mir-4451 ; hsa-mir-6799-5p ; hsa-mir-765 ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-mir-6804-5p ; hsa-let-7a-5p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-3663-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-4739 ; hsa-mir-6873-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-597-5p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6778-3p ; hsa-mir-6747-3p ; hsa-mir-4740-3p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-3622a-5p ; hsa-mir-4438 ; hsa-mir-4776-3p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-483-3p ; hsa-mir-3159 ; hsa-mir-3167 ; hsa-mir-361-3p ; hsa-mir-4446-5p ; hsa-mir-4755-5p ; hsa-mir-5006-3p ; hsa-mir-670-5p ; hsa-mir-6752-3p ; hsa-mir-6791-3p ; hsa-mir-6793-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-876-5p
Nearest miRNA
hsa-mir-141/Upstream/139530; hsa-let-7i/Downstream/2135746;
Nearest TSS
ENST00000382841/Upstream/1636; ENST00000536679/Downstream/4331;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/84669, chr12-CpG: 64/Downstream/85757
Upstream sequence
atgtgtaagatactgtgctaggtgctggggacacagatgtgacaaaggcacagttctgctcccgaggagcagtggctgaggacgctgacaagtaaaaaaa
Downstream sequence
taaactagattatagtgtgctgaatTCTGCCTTTGAGGGGTGTGTGTGTGTGACTTACTCTGGGAGGAATCCTTTTTCTGAACTTGAAGTTTCTCAATGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate