Basic Information
VIS ID
TVIS44029618
Fusion event
HTLV-1-ATP8A1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
p13
Reference genome
NCBI36/hg18
Start
42282640/42585866 (Hg38)
End
42282640/42585866 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATP8A1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-181a-5p ; hsa-mir-140-3p
Nearest miRNA
hsa-mir-12113/Upstream/2083747; hsa-mir-1243/Downstream/5066803;
Nearest TSS
ENST00000502981/Upstream/29631; ENST00000562054/Downstream/2751;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/187081, chr4-CpG: 116/Downstream/70395
Upstream sequence
actggttgaatgaatgaGGGAAGGGGTAGAAGAGAAGAAACAAGAGAGGCAGGAAGCAGGTAACAAAAAGAGATGAGATGACTATAATTAATACCACAGG
Downstream sequence
CTAGAAAGAACATTTGAAATTTCATGGAGGAGACAATAAATTATCCAGTACAATAGACCCCTTGAAGGTAGAGTCTGAACTCCTTGAAGCATCTCAAGAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate