Basic Information
VIS ID
TVIS44029622
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
97486932/97248788 (Hg38)
End
97486932/97248788 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1M
Target gene
DPYD ; DPYD-AS1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-302b-3p ; hsa-mir-494-5p
Nearest miRNA
hsa-mir-101-1/Upstream/2705009; hsa-mir-11399/Downstream/796454;
Nearest TSS
ENST00000473358/Upstream/152865; ENST00000629811/Downstream/16658;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/526525, chr1-CpG: 47/Downstream/671845
Upstream sequence
tgagactatcctcaatctgacaaagaacatctataaaaaaacctatagctaaaatcagactttatgttaaaaaattctttctctATATACTCTTCATACT
Downstream sequence
TTCTATATACTCTAttccatatactcacaagaagcaattagaaagttaaaaaatagtattcacaatagcaccaaaaagcaacaataggagtacatttaga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate