Basic Information
VIS ID
TVIS44029623
Fusion event
HTLV-1-JMJD1C integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
64847007/63417241 (Hg38)
End
64847007/63417241 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
JMJD1C
miRNAs that regulate target gene
hsa-mir-326 ; hsa-let-7e-5p ; hsa-mir-374a-5p ; hsa-mir-718 ; hsa-mir-587 ; hsa-mir-6084 ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-145-3p ; hsa-mir-6880-3p ; hsa-mir-4485-5p ; hsa-mir-2681-5p ; hsa-mir-5579-3p ; hsa-mir-889-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-590-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-23c ; hsa-mir-130a-5p ; hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-627-3p ; hsa-mir-205-5p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-6875-3p ; hsa-mir-670-3p ; hsa-mir-4762-5p ; hsa-mir-513b-3p ; hsa-mir-3662
Nearest miRNA
hsa-mir-1265/Upstream/44193; hsa-mir-107/Downstream/3986110;
Nearest TSS
ENST00000439456/Upstream/147988; ENST00000609436/Downstream/47988;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/283665, chr10-CpG: 122/Downstream/47869
Upstream sequence
aaccatcttgaaaatatttcacagcctacaactcaggaaacttgcccaattatttaaacaagtaattgaATGCAACCGGTTATCAAAGAATTGGAAGTTA
Downstream sequence
AATATGTTAAGAAGCATGCTCAATGTACATACATAGATGACGTACTACTATATTGGGTTTTTAAAAGCAGAAATTAAATTAAAGCTCAACTTAAAATGCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate