Basic Information
VIS ID
TVIS44029642
Fusion event
HTLV-1-MRPL50 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
103199888/101397785 (Hg38)
End
103199888/101397785 (Hg38)
Orient
+
Location type
Intronic
Target gene
MRPL50
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-125a-5p ; hsa-mir-1305 ; hsa-mir-335-3p ; hsa-mir-4698 ; hsa-mir-4735-5p ; hsa-mir-4775 ; hsa-mir-576-5p ; hsa-mir-590-3p ; hsa-mir-6074 ; hsa-mir-607 ; hsa-mir-8063
Nearest miRNA
hsa-let-7a-1/Upstream/3168568; hsa-mir-12126/Downstream/5203143;
Nearest TSS
ENST00000422679/Upstream/14266; ENST00000615466/Downstream/829;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/368303, chr9-CpG: 49/Downstream/786
Upstream sequence
AAGAGGGAAAGCTAATATCTGAACTGATGAAAAAGATCTTTCCTAATTGTAGTGGTTTTTGTTTTAAACCTAAGAGAGCATACATTGCTCCCTAGGGTTC
Downstream sequence
CTACCATACGTTTTGATTTCCTAAACACTATCTAAGTCAAATTAGATTTACCTTCAAACAATTACACATGGTgcagccgtgcagcagaaaaagcagtaga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate