Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene466577324654180646583121465809374661711946568256465802384656737346571702465466014655019046563914465671424655765846560871465826604658572546587375465901904657886046581204465611464656255646573978465752364655417546555311465630014656340046551692465519984656256246562711465672224656737146599769
Basic Information
VIS ID
TVIS44029651
Fusion event
HTLV-1-PIGF integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p21
Reference genome
NCBI36/hg18
Start
46680412/46599769 (Hg38)
End
46680412/46599769 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
PIGF
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-145-5p
Nearest miRNA
hsa-mir-1301/Upstream/11128283; hsa-mir-10b/Downstream/777906;
Nearest TSS
ENST00000437798/Upstream/11147; ENST00000486447/Downstream/12505;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/56120, chr2-CpG: 64/Downstream/16742
Upstream sequence
atgatctcatctttgctcttaatttattcaattcatatccttagtactatttttcatggtaaactgtgtggaggtttttttgtttatttttgcttctagg
Downstream sequence
gtagcactttctttcaggccagattcttcatcttctgcacaccccttttccttcttctatagtgcatttttagggttgtcatgccgtttcttttctcttg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate