Basic Information
VIS ID
TVIS44029659
Fusion event
HTLV-1-PCNX1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q24.2
Reference genome
NCBI36/hg18
Start
70466851/70930381 (Hg38)
End
70466851/70930381 (Hg38)
Orient
+
Location type
Intronic
Target gene
PCNX1
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-17-5p ; hsa-mir-3941 ; hsa-mir-374a-5p ; hsa-mir-510-3p ; hsa-mir-6831-3p ; hsa-mir-4637 ; hsa-mir-590-3p ; hsa-mir-4282 ; hsa-mir-2355-3p ; hsa-mir-4646-3p ; hsa-mir-3912-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5688 ; hsa-mir-495-3p
Nearest miRNA
hsa-mir-208a/Upstream/3488451; hsa-mir-1185-1/Downstream/1586439;
Nearest TSS
ENST00000550708/Upstream/22642; ENST00000553508/Downstream/16501;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/21696, chr14-CpG: 116/Downstream/389757
Upstream sequence
gctacaggcgaatgtcactgtacctggcTTCATATGGATCAAGCTGCTCATCTCTAACTCCTGGCTTAGTGACTTCTGCCCTGAGTAATAGACTCAATCT
Downstream sequence
CTGTTGCCGATGAGTTGCATGTGCTATGTTATTTTAGTCTCTTTTCAGCTAGGTGATGTGGCATAAATTTTGACTGTTACCTCCCTAAGAACAGCATTCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate