Basic Information
VIS ID
TVIS44029673
Fusion event
HTLV-1-VPS13A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q21.2
Reference genome
NCBI36/hg18
Start
79019481/77214745 (Hg38)
End
79019481/77214745 (Hg38)
Orient
+
Location type
Intronic
Target gene
VPS13A
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-15b-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4326 ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-138-2-3p
Nearest miRNA
hsa-mir-101-2/Upstream/6404661; hsa-let-7a-1/Downstream/6755003;
Nearest TSS
ENST00000422679/Upstream/5257; ENST00000423463/Downstream/65101;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/36333, chr9-CpG: 108/Downstream/432785
Upstream sequence
GGATTATTCAGTAACAATTAGGGTAATATTTATGAAGACATTTCAAAATGGCAAGTAAAATTTAATAAGGCTAGCTAGTACAGCCTTTTTCGAAATAGTA
Downstream sequence
AGATCACGCTGCATTTAAAAtttttttaatttatacttttctatgttttcctaattttccaaaatgagcatccattacttttacaatcggaaaTGAATTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate