Basic Information
VIS ID
TVIS44029674
Fusion event
HTLV-1-PRORP integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q13.2
Reference genome
NCBI36/hg18
Start
34796448/35257491 (Hg38)
End
34796448/35257491 (Hg38)
Orient
-
Location type
Intronic
Target gene
PRORP
miRNAs that regulate target gene
hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-2117 ; hsa-mir-148a-5p ; hsa-mir-7856-5p ; hsa-mir-3658 ; hsa-mir-744-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-431-5p ; hsa-mir-193a-5p ; hsa-mir-31-3p ; hsa-mir-4524a-3p ; hsa-mir-4726-3p ; hsa-mir-4781-3p ; hsa-mir-1182 ; hsa-mir-4524b-3p ; hsa-mir-1273e ; hsa-mir-8065 ; hsa-mir-4656 ; hsa-mir-7160-5p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4721 ; hsa-mir-4699-5p ; hsa-mir-7162-3p ; hsa-mir-4446-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-203b-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p
Nearest miRNA
hsa-mir-208a/Upstream/4242749; hsa-mir-1185-1/Downstream/1694818;
Nearest TSS
ENST00000550708/Upstream/134732; ENST00000628955/Downstream/21142;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/134694, chr14-CpG: 31/Downstream/34703
Upstream sequence
ttctatgctgtctttatgaatttgactactttaggtaacttatgtaagtgcaatcattcagtatttgtcctttagtgtctggcttttttcacttagtttt
Downstream sequence
caagttcatccatgttgtagcatgtattagaatttcattcctgtttaaggctgaataataatctattatatgtatataccacattttatcgatctattca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate