Basic Information
VIS ID
TVIS44029688
Fusion event
HTLV-1-CDK5RAP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q33.2
Reference genome
NCBI36/hg18
Start
122340788/120538689 (Hg38)
End
122340788/120538689 (Hg38)
Orient
-
Location type
Intronic
Target gene
CDK5RAP2
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-324-3p ; hsa-mir-149-5p
Nearest miRNA
hsa-let-7a-1/Upstream/293639; hsa-mir-12126/Downstream/1581393;
Nearest TSS
ENST00000422679/Upstream/2252; ENST00000437707/Downstream/431;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/43593, chr9-CpG: 41/Downstream/41159
Upstream sequence
aaaggtcagagtctggttccaggcttgactaatgttaggtaagtcatttcccttctctggccgtcagcttccacatctttaaaataatggggctaaacta
Downstream sequence
gacaagcagagtggtgctgtaggaagagcatgggctttaaaatccgcatagttaaacccaggattaaacctactagtattaggttaagcctattaaacga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate