Basic Information
VIS ID
TVIS44029702
Fusion event
HTLV-1-CELF2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
NCBI36/hg18
Start
10835595/10753626 (Hg38)
End
10835595/10753626 (Hg38)
Orient
+
Location type
Intronic
Target gene
CELF2
miRNAs that regulate target gene
hsa-mir-425-5p ; hsa-mir-375 ; hsa-mir-324-5p ; hsa-let-7e-5p ; hsa-mir-95-3p ; hsa-mir-4717-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-192-3p ; hsa-mir-124-5p ; hsa-mir-4275 ; hsa-mir-203a-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-642a-5p ; hsa-mir-329-5p ; hsa-mir-4748 ; hsa-mir-4464
Nearest miRNA
hsa-mir-3155a/Upstream/4601349; hsa-mir-107/Downstream/1377134;
Nearest TSS
ENST00000439456/Upstream/291277; ENST00000420825/Downstream/35410;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/487000, chr10-CpG: 158/Downstream/263853
Upstream sequence
AAAGTGAGCCCACTCCCAGACCAGAAATGTATCCAAGGACCGGGAAACACACTACCATGTTAATCAATTATATAGCTTTCTTCTTGGACAACTTAAGTAG
Downstream sequence
CATTTCTCTTTCTTATATTAAAAAATCACAAGTCTTTTGAGAGAACTTATAAGATGAACAGTTGACTTTTGAAACAGTAAAATTCTTCCTAATTTTCCTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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