Basic Information
VIS ID
TVIS44029709
Fusion event
HTLV-1-ASAP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
NCBI36/hg18
Start
131373027/130291599 (Hg38)
End
131373027/130291599 (Hg38)
Orient
-
Location type
Intronic
Target gene
ASAP1
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-mir-106b-5p ; hsa-mir-203a-3p ; hsa-mir-136-5p ; hsa-mir-544a ; hsa-mir-136-3p ; hsa-mir-432-5p ; hsa-mir-493-3p ; hsa-mir-208a-3p ; hsa-mir-208b-3p ; hsa-mir-27b-5p ; hsa-mir-3138 ; hsa-mir-3148 ; hsa-mir-4432 ; hsa-mir-4463 ; hsa-mir-4520-3p ; hsa-mir-4635 ; hsa-mir-4720-3p ; hsa-mir-499a-5p ; hsa-mir-6124 ; hsa-mir-6864-5p ; hsa-mir-8071 ; hsa-mir-8087 ; hsa-mir-875-3p
Nearest miRNA
hsa-mir-1204/Upstream/283146; hsa-mir-10400/Downstream/2754882;
Nearest TSS
ENST00000518652/Upstream/44557; ENST00000523318/Downstream/49338;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/274750, chr8-CpG: 135/Downstream/66242
Upstream sequence
GAGACACTGACAAAACAATAATACTTATTACCTTCCTATCTCCCTCAGGGTTTCGGTgagaagagagatgaggggaggagggaaaagaagaggggaaaag
Downstream sequence
gaaggggaagaggagGCTGATAAGTTTGACGAGTGAGTGAGAAAGTAAAGGGACATAAATGAGTGGACTGAATAAATATGTTTCATACATACCTTGAAAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate