Basic Information
VIS ID
TVIS44029718
Fusion event
HTLV-1-RNF217 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q22.31
Reference genome
NCBI36/hg18
Start
125367507/125004662 (Hg38)
End
125367507/125004662 (Hg38)
Orient
+
Location type
Intronic
Target gene
RNF217
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-4276 ; hsa-mir-205-5p ; hsa-mir-5190 ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-138-2-3p ; hsa-mir-6507-5p ; hsa-mir-6833-5p ; hsa-mir-6124 ; hsa-mir-3190-3p ; hsa-mir-3148 ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-4280 ; hsa-mir-576-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-198 ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-4530 ; hsa-mir-590-3p ; hsa-mir-338-3p ; hsa-mir-6818-3p ; hsa-mir-4279 ; hsa-mir-6881-3p ; hsa-mir-6895-3p ; hsa-mir-593-3p ; hsa-mir-6845-3p ; hsa-mir-942-5p ; hsa-mir-877-3p
Nearest miRNA
hsa-mir-10398/Upstream/4989405; hsa-mir-1202/Downstream/1479969;
Nearest TSS
ENST00000381078/Upstream/21294; ENST00000431104/Downstream/4093;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/41419, chr6-CpG: 34/Downstream/94935
Upstream sequence
AAAGGTAGGTACAGAAGTGTTCTAAGTTGGGATAGTATCACTGGGAGAAGAACAAGGCTTCTAGTGAAGTGCTGTGAAGGCCTAAGTCTTTTTAAATGAT
Downstream sequence
CCTCTGTTTCACTTGTTGTTGAAAGGGAAAGTTAAAATTATAAATGCCTAAATATATGCACAAAGGACAAGAACCACAGCTCGTGTGTAATTCTGGTGTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate