Basic Information
VIS ID
TVIS44029746
Fusion event
HTLV-1-ERH integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
NCBI36/hg18
Start
68932361/69395891 (Hg38)
End
68932361/69395891 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA14C
Target gene
ERH
miRNAs that regulate target gene
hsa-mir-92a-3p ; hsa-mir-4709-3p ; hsa-mir-1257 ; hsa-mir-340-5p ; hsa-mir-3185 ; hsa-mir-4635 ; hsa-mir-4501 ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-3154 ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-3935
Nearest miRNA
hsa-mir-208a/Upstream/1953961; hsa-mir-1185-1/Downstream/3120929;
Nearest TSS
ENST00000550708/Upstream/965; ENST00000554059/Downstream/2124;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/134215, chr14-CpG: 44/Downstream/2105
Upstream sequence
TTACTGGGCTTTCTCATACCAAAATCACATATTAGAATCACACAGAAAGTTAGGTCATCACACTATGAGAAATGTGAAATAATGCCCATAGCAGACAGAC
Downstream sequence
TTGTCTTCCACTTCGTGCTCACTGGGAAACATGTTTTTGTTAGTGATCAGTCACTAACAAATCAATCTCAGTGTTTTCTCAACGTGGGCTCTATTACCTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate