Basic Information
VIS ID
TVIS44029759
Fusion event
HTLV-1-ROBO2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
NCBI36/hg18
Start
76213858/76082017 (Hg38)
End
76213858/76082017 (Hg38)
Orient
-
Location type
Intronic
Target gene
ROBO2
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-342-5p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-6844 ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-8084
Nearest miRNA
hsa-let-7g/Upstream/343654; hsa-mir-12124/Downstream/3425870;
Nearest TSS
ENST00000440867/Upstream/175215; ENST00000475034/Downstream/229079;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/174860, chr3-CpG: 63/Downstream/957330
Upstream sequence
GAAGTGTAGACATGCATATAAAATATAACTTTATTTTGCTAATGAAATTAGAATCAAGCCACAGATTTTTGTGACTGGCAAAGATAATTGAGCCCCCAAC
Downstream sequence
CGTTAATCTCCTTTCTTCACTCCAAGCTACTTGATTGATTCTACAAACATATTTACTATCTACAAGCATCAGTCACTGAGCCGTATGCCCAAATAAATGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate