Basic Information
VIS ID
TVIS44029764
Fusion event
HTLV-1-EYS integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
NCBI36/hg18
Start
64857014/64089162 (Hg38)
End
64857014/64089162 (Hg38)
Orient
-
Location type
Intronic
Target gene
EYS
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-510-3p ; hsa-mir-376a-5p ; hsa-mir-4680-5p ; hsa-mir-494-3p
Nearest miRNA
hsa-mir-10398/Upstream/6698950; hsa-mir-10524/Downstream/7287798;
Nearest TSS
ENST00000381078/Upstream/22786; ENST00000424274/Downstream/288633;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/452602, chr6-CpG: 22/Downstream/1212198
Upstream sequence
GTTTTTGTTGAGTAGTTTTTCACCTTCCCCAGAAAGGACATCGTACAAACTCTGTGACGAAGTTTATAAAAAAGAAGGTGACTGAAATGATGCaattatt
Downstream sequence
attttaatttaaaaatattaCATTTTCCACTTATGAGTCTAATTTTATTAAAATCTGTGATTTAAATGAATATCACCAGTTTATAAGTCCATGTATCTCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate