Basic Information
VIS ID
TVIS44029766
Fusion event
HTLV-1-EFHC2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
p11.3
Reference genome
NCBI36/hg18
Start
44038105/44293915 (Hg38)
End
44038105/44293915 (Hg38)
Orient
+
Location type
Intronic
Target gene
EFHC2
miRNAs that regulate target gene
hsa-mir-3689d ; hsa-mir-4443 ; hsa-mir-4455 ; hsa-mir-574-5p ; hsa-mir-6515-5p ; hsa-mir-6767-3p ; hsa-mir-6851-5p ; hsa-mir-6867-5p
Nearest miRNA
hsa-mir-1587/Upstream/4456302; hsa-let-7f-2/Downstream/1452242;
Nearest TSS
ENST00000429181/Upstream/68159; ENST00000339042/Downstream/49757;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/411334, chrX-CpG: 24/Downstream/16349
Upstream sequence
ctttctatgctatggatacacataaatccttcctcttacccatagggctatcttcagacctatttgacattttcaacaatatctttacaccacagagcag
Downstream sequence
agaataagcaaaaatacacaatgagtaatgcacgaaggtcttggtcctacacggggaattgtggggaacgtgccgttggcatatccagcctgcacatgtg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate