Basic Information
VIS ID
TVIS44029771
Fusion event
HTLV-1-RHBDL3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
27663804/32312672 (Hg38)
End
27663804/32312672 (Hg38)
Orient
+
Location type
Intronic
Target gene
RHBDL3
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-521 ; hsa-mir-8485 ; hsa-mir-33a-3p
Nearest miRNA
hsa-mir-1180/Upstream/737151; hsa-mir-10226/Downstream/37437;
Nearest TSS
ENST00000595228/Upstream/28520; ENST00000580360/Downstream/15769;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/45658, chr17-CpG: 25/Downstream/29334
Upstream sequence
agtggcgcaatatcgtctcactgcagcctccacctcccaggttcaagcaattcttgtgcctcagcctccagagtagctggggttacaggcatgtaccacc
Downstream sequence
acacccagctaatttttttatatgtttagtagagatggggttttgctgtttgccaggctggtcttgagctcctggcctcaagtgatccgcctgcgtcagc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate