Basic Information
VIS ID
TVIS44029774
Fusion event
HTLV-1-RABL3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q13.33
Reference genome
NCBI36/hg18
Start
121942062/120740525 (Hg38)
End
121942062/120740525 (Hg38)
Orient
-
Location type
Intronic
Target gene
RABL3
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-4275 ; hsa-mir-4788 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-6793-3p ; hsa-mir-6729-3p ; hsa-mir-8485 ; hsa-mir-329-3p ; hsa-mir-362-3p ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-6883-3p ; hsa-mir-4755-5p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-4524a-3p ; hsa-mir-6823-5p ; hsa-mir-454-5p ; hsa-mir-4781-3p ; hsa-mir-4524b-3p ; hsa-mir-3149 ; hsa-mir-1297 ; hsa-mir-1306-5p ; hsa-mir-150-5p ; hsa-mir-1915-3p ; hsa-mir-1976 ; hsa-mir-26a-5p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4465 ; hsa-mir-4722-3p ; hsa-mir-4726-3p ; hsa-mir-562 ; hsa-mir-5697 ; hsa-mir-6513-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6764-5p ; hsa-mir-6778-3p ; hsa-mir-6814-5p ; hsa-mir-6840-3p ; hsa-mir-8062
Nearest miRNA
hsa-let-7g/Upstream/344796; hsa-mir-12124/Downstream/309115;
Nearest TSS
ENST00000440867/Upstream/29979; ENST00000484715/Downstream/1980;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/143882, chr3-CpG: 62/Downstream/167508
Upstream sequence
aactttctgtactgtttttggtagagagagggtcttgccatgttgcccaggctagtcttgaactgagctcaagcaatccacccgcctcaacctcccaaag
Downstream sequence
tgctgggattataggctagagccaccttgtctggctAAGTCATTTCTTTATATATTTGTGAAACCCTCAAAATTTTATAAGGGAAATGGCCTTTATTTAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate