Basic Information
VIS ID
TVIS44029785
Fusion event
HTLV-1-ACP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
NCBI36/hg18
Start
260622/270622 (Hg38)
End
260622/270622 (Hg38)
Orient
+
Location type
Intronic
Target gene
ACP1
miRNAs that regulate target gene
hsa-mir-151a-3p ; hsa-mir-25-3p ; hsa-mir-595 ; hsa-mir-648 ; hsa-mir-3115 ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-5680 ; hsa-mir-6513-3p ; hsa-mir-6868-3p ; hsa-mir-371a-5p ; hsa-mir-205-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-609 ; hsa-mir-6772-5p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-6882-5p
Nearest miRNA
hsa-mir-10b/Downstream/5704040;
Nearest TSS
ENST00000437798/Upstream/4224; ENST00000463831/Downstream/3951;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/5384, chr2-CpG: 263/Downstream/16731
Upstream sequence
TTGCTTTGTAGCATCGTTCTTTTTCTGTGCTGCTGTAGTGTATTGTTTATCAGCATTCATTTTCCCACttttattataataaatataataaataaaGtgg
Downstream sequence
agatagagttcagctgaatggccagtgattcaacccattgtgtctccctccgaaaaccccaataaaacctcagagcactatggctctgaggagcttcctg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate