Basic Information
VIS ID
TVIS44029795
Fusion event
HTLV-1-NUTF2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
66462888/67871484 (Hg38)
End
66462888/67871484 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
NUTF2
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-193b-3p ; hsa-mir-19b-3p ; hsa-mir-203a-5p ; hsa-mir-4282 ; hsa-mir-1273g-5p ; hsa-mir-203b-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-3658 ; hsa-mir-5701 ; hsa-mir-3653-3p ; hsa-mir-96-3p ; hsa-mir-2681-3p ; hsa-mir-548g-3p ; hsa-mir-548av-3p
Nearest miRNA
hsa-mir-1225/Upstream/669089; hsa-mir-11401/Downstream/361942;
Nearest TSS
ENST00000527434/Upstream/1524; ENST00000572031/Downstream/1539;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/23871, chr16-CpG: 65/Downstream/1422
Upstream sequence
TCATGTTTCACCCTCCCACTTCTGCCCCAACTCTGAATACCTGTTGCAGGGAGAAACTGCTGAAGCAGCACTCCCAGCTAGCCTCTCAGAAGCCGTGTAG
Downstream sequence
GGCAGTTCTCTCCCACTCCACAGGGCGACTGGTCTTTGGAAAGCAGGCAGGAAGAGCTCAGGTCTGGCCTGAAGCTTCTCTCACTGAAGCCTGTGCAGTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate