Basic Information
VIS ID
TVIS44029796
Fusion event
HTLV-1-TMPRSS15 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
NCBI36/hg18
Start
18650850/18356662 (Hg38)
End
18650850/18356662 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMPRSS15
miRNAs that regulate target gene
hsa-mir-6864-3p ; hsa-mir-578 ; hsa-mir-3672 ; hsa-mir-526b-5p ; hsa-mir-873-3p ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-654-3p ; hsa-mir-548c-3p
Nearest miRNA
hsa-let-7c/Upstream/1766337; hsa-mir-155/Downstream/329428;
Nearest TSS
ENST00000624081/Upstream/100160; ENST00000416002/Downstream/46994;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/111105, chr21-CpG: 89/Downstream/2640443
Upstream sequence
TTGCCAGGCACTATGATTGGCGAATCTTTGAGAATTTCTGGAAGGGATGACTTAAGCAAACTTAGTGCTTGCTAAAATAAACTTTTCCACATAACATACC
Downstream sequence
CCTATCAACAGAAGTGAATTAATGGGTACTTCTGAGTATACATAAAAGTGTCCTAATAAAAGCACAAAATGTGTTGAAAATGCTTTACTTTGAATAATAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate