Basic Information
VIS ID
TVIS44029798
Fusion event
HTLV-1-PKP4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
NCBI36/hg18
Start
159057473/158492715 (Hg38)
End
159057473/158492715 (Hg38)
Orient
+
Location type
Intronic
Target gene
PKP4
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-218-5p ; hsa-mir-449a
Nearest miRNA
hsa-mir-128-1/Upstream/7124304; hsa-mir-10b/Downstream/694120;
Nearest TSS
ENST00000437798/Upstream/34522; ENST00000629219/Downstream/40470;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/34414, chr2-CpG: 146/Downstream/475627
Upstream sequence
ACTTGACAACCCACTCCATGGGAAAATTGCTTTCCTTCTTTGCCTGTTACAATAGTATTTTTTTCTGTCTCCTTTTGTCTTTCTGACTCTTACTACTTAA
Downstream sequence
GTTCTGTTTCCAGCTGACCATTTTCCTCCTGCGTACCTTTTAACATTACTATTTTCTTCTTCTTACAGAAGTGTTATACGTGTTTACAGTAGAAAATGCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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