Basic Information
VIS ID
TVIS44029805
Fusion event
HTLV-1-ZC4H2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
64114058/64977453 (Hg38)
End
64114058/64977453 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZC4H2
miRNAs that regulate target gene
hsa-mir-152-5p ; hsa-mir-597-3p ; hsa-mir-182-3p ; hsa-mir-4539 ; hsa-mir-218-2-3p
Nearest miRNA
hsa-let-7f-2/Upstream/1191366; hsa-mir-105-1/Downstream/1041417;
Nearest TSS
ENST00000429181/Upstream/920; ENST00000617377/Downstream/57216;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/581910, chrX-CpG: 78/Downstream/57075
Upstream sequence
AGGTGTAGAGGTGGAAAAAAGAAATGGGAGATGTAGTATTTAGAAAAGGCAGGTAGGAACCAGACTATGAAATACGTTAAATGTCAGACTAAAGGGTTTG
Downstream sequence
GACTTAATCCTGTAGGCAGACATTTATCTAATAAACTTTTAAATTAATTAAtttatttatttatgagacagtctcactctgtcgcccaagctggcgtgta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate