Basic Information
VIS ID
TVIS44029809
Fusion event
HTLV-1-H2AFV integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
NCBI36/hg18
Start
44839950/44833826 (Hg38)
End
44839950/44833826 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7D
Target gene
H2AFV
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-100-5p ; hsa-mir-17-3p ; hsa-mir-136-5p ; hsa-mir-299-5p
Nearest miRNA
hsa-mir-1183/Upstream/722914; hsa-mir-10399/Downstream/47922;
Nearest TSS
ENST00000635602/Upstream/35012; ENST00000450016/Downstream/14195;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/36627, chr7-CpG: 72/Downstream/13842
Upstream sequence
agtcagccagatctaggtttgaatcctagctctgtcattttctatctaccagttcaatgttttttggcatagcacacaatttctgtgacccttaggctcc
Downstream sequence
acatctataatgtggcagcaacaactttcttggtcagtagagcactctgcaaagggcctggcacatggtaagtgctTGGTGTAGAATTCAAATAATTCCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate