Basic Information
VIS ID
TVIS44029810
Fusion event
HTLV-1-STX11 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q24.2
Reference genome
NCBI36/hg18
Start
144535154/144172324 (Hg38)
End
144535154/144172324 (Hg38)
Orient
+
Location type
Intronic
Target gene
STX11
miRNAs that regulate target gene
hsa-mir-373-3p ; hsa-mir-15b-3p ; hsa-mir-3185 ; hsa-mir-5188 ; hsa-mir-136-3p
Nearest miRNA
hsa-mir-10398/Upstream/3488441; hsa-mir-1202/Downstream/6930351;
Nearest TSS
ENST00000381078/Upstream/21798; ENST00000433557/Downstream/113377;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/21444, chr6-CpG: 88/Downstream/14365
Upstream sequence
atgtaaaccttccacaacagtctctggcagatagtaagcacCTGTGATTCTTCTACGGATCTCACCTGGACTCAGTCATGCAgctgtagaggtgggtcag
Downstream sequence
ctgggggctggcctagctctccgtgcggtcttcaccctccaggaggctagtctgagctttctcacataatggtttcagtgttcccagagcagataagccc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate