Basic Information
VIS ID
TVIS44029824
Fusion event
HTLV-1-LVRN integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
NCBI36/hg18
Start
115383489/116019893 (Hg38)
End
115383489/116019893 (Hg38)
Orient
-
Location type
Intronic
Target gene
LVRN
miRNAs that regulate target gene
hsa-mir-1305 ; hsa-mir-653-5p ; hsa-mir-7158-3p ; hsa-mir-203b-3p ; hsa-mir-627-3p ; hsa-mir-676-5p ; hsa-mir-409-3p
Nearest miRNA
hsa-mir-10397/Upstream/5505978; hsa-mir-103a-1/Downstream/235850;
Nearest TSS
ENST00000502646/Upstream/5473; ENST00000506279/Downstream/1134;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/56453, chr5-CpG: 61/Downstream/64991
Upstream sequence
AGAGGCAGCTTGCCTAAATGCAAAAACAAACAAATACCATCTCAGGTCCAGCTTGGCCCTGGGCATGAAGTGACCAGTGCTGTGGTTTTGAGTACATCTC
Downstream sequence
TCCCTTGTCTCAGAGCATTCATGGGCATATGTCTCACAGTGACATGCAGGCAAGCTCACAGACATCGTCTCCACACCAAGGCACATGTTGGAGTTGAGTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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