Basic Information
VIS ID
TVIS44029830
Fusion event
HTLV-1-MARCH1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q32.3
Reference genome
NCBI36/hg18
Start
165288991/164148389 (Hg38)
End
165288991/164148389 (Hg38)
Orient
+
Location type
Intronic
Target gene
MARCH1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-4446-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-337-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-8068 ; hsa-mir-5087 ; hsa-mir-6832-3p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-202-5p
Nearest miRNA
hsa-mir-12113/Upstream/1054761; hsa-mir-1305/Downstream/1237853;
Nearest TSS
ENST00000502981/Upstream/12892; ENST00000515485/Downstream/235128;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/653355, chr4-CpG: 36/Downstream/39893
Upstream sequence
AATTCCAAAATCAATCAATATCAAAATGAACACAAATGACAGCAGATAATTCAGACTCTTGAAGAAAATGTCATACCCCATAGATCTTGGTTAAGTAATC
Downstream sequence
CTTTACTGCTAATGATGGCCAGCCATGTTCTCTTAATTTTTTTTTCCATGTTCTCTTAATTAATCTTTATCCCATTCTACCATTTCTTTATCCTTTTCCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate