Basic Information
VIS ID
TVIS44029831
Fusion event
HTLV-1-KCNMA1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
NCBI36/hg18
Start
79026096/77596332 (Hg38)
End
79026096/77596332 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
KCNMA1
miRNAs that regulate target gene
hsa-mir-211-5p ; hsa-mir-218-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1265/Upstream/2043779; hsa-mir-107/Downstream/8668362;
Nearest TSS
ENST00000439456/Upstream/97362; ENST00000600739/Downstream/41003;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1483785, chr10-CpG: 220/Downstream/40005
Upstream sequence
ctgtggacagggacactggttcctctccagagatcaatttcataatatctatcaacttgtaaatggcaagtccctttcaattcagcaattccacttctag
Downstream sequence
aaatctatccaaaagaaatcctcatacatgcataaaaagactcatacacaagattattcattgtttgaagtgcaacagatgggacatggcctaaatgtcc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate