Basic Information
VIS ID
TVIS44029841
Fusion event
HTLV-1-AGMO integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p21.2
Reference genome
NCBI36/hg18
Start
15246354/15240204 (Hg38)
End
15246354/15240204 (Hg38)
Orient
+
Location type
Intronic
Target gene
AGMO
miRNAs that regulate target gene
hsa-mir-5698 ; hsa-mir-6738-3p ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-143-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-6499-3p ; hsa-mir-6777-3p ; hsa-mir-483-3p ; hsa-mir-3145-5p ; hsa-mir-3680-5p ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p
Nearest miRNA
hsa-mir-339/Upstream/8173159; hsa-mir-10399/Downstream/2887016;
Nearest TSS
ENST00000635602/Upstream/173997; ENST00000451240/Downstream/125983;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1248616, chr7-CpG: 17/Downstream/1159293
Upstream sequence
AGCTACATCAAAGGGGTAATATAATGAAATAAACATCTATTTATTCAATACATGCTAACTACCTGGTGTGTTAGGTCTCTTCATATtaggcttgccatat
Downstream sequence
ttaaaaaataaaaatacaggacgacaagttaagtttgaattgtagataaaccataaatatatttttagcataaatatgtgtcatgcaatattagaacgta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate