Basic Information
VIS ID
TVIS44029845
Fusion event
HTLV-1-ARFIP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
NCBI36/hg18
Start
153923905/152783303 (Hg38)
End
153923905/152783303 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARFIP1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-23b-3p ; hsa-mir-877-3p
Nearest miRNA
hsa-mir-12113/Upstream/246787; hsa-mir-1305/Downstream/6345499;
Nearest TSS
ENST00000502981/Upstream/3194; ENST00000513361/Downstream/67340;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2964, chr4-CpG: 232/Downstream/152657
Upstream sequence
aggggctgaggcaggagaatcgcttgaacccaggaggcggaggctgcagtaagccaagatcccaccacttcactccagcctggccaacagagtgagactc
Downstream sequence
catctcaaaaaCAACATCAACAACAGACTAGCTTATGCTAAATTAGTTTCCTTTTAAGGTAATGACAAATTCGGAAGATATTTTATATCTAACACTGTAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate