Basic Information
VIS ID
TVIS44029846
Fusion event
HTLV-1-ABLIM2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
p16.1
Reference genome
NCBI36/hg18
Start
8150344/8097717 (Hg38)
End
8150344/8097717 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4A
Target gene
ABLIM2
Nearest miRNA
hsa-mir-378d-1/Upstream/92336; hsa-mir-12113/Downstream/1458451;
Nearest TSS
ENST00000502981/Upstream/25731; ENST00000504822/Downstream/60972;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/370, chr4-CpG: 24/Downstream/54633
Upstream sequence
CCTGAGCCCCTGCTGTCCTCCAGTGGGCTGTTTCCAGCACTGGGCATACAGATCAGGAAGGGGCTAATGCctgatcacctactgtgtgctagactctgtg
Downstream sequence
ctgggggccgaaggttcccaggaggacagaccaggtccttgtggtcggtgcctccagcccaCCTCTAGGCTTCCCACCCCCTCCCCCACTCCTCTGGGTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate