Basic Information
VIS ID
TVIS44029856
Fusion event
HTLV-1-NRG1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
NCBI36/hg18
Start
32634029/32656968 (Hg38)
End
32634029/32656968 (Hg38)
Orient
-
Location type
Intronic
Target gene
NRG1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-125a-3p
Nearest miRNA
hsa-mir-124-1/Upstream/2699620; hsa-mir-10400/Downstream/8614080;
Nearest TSS
ENST00000518652/Upstream/9130; ENST00000523681/Downstream/64785;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/107585, chr8-CpG: 60/Downstream/815678
Upstream sequence
ATTTTTCATCAGAAACATGATAGGACAAGACTTGATTTACTGTGATTTTCAGTGATAGGCACTTAGTGTTTGAGTTGCATTTCATGAGGTGGTTGTCTCC
Downstream sequence
CAGCCAAAGGAGAAATTCATGAACTCTCTTTGAAGCCAGAGTTAGCACAGAATTTAATATGCATGTAATTATCAAATGTAAAAATCTTCataatttattt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate