Basic Information
VIS ID
TVIS44029865
Fusion event
HTLV-1-SLC3A2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q12.3
Reference genome
NCBI36/hg18
Start
62390902/62866854 (Hg38)
End
62390902/62866854 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC3A2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-193b-3p ; hsa-mir-10a-5p ; hsa-mir-92a-3p ; hsa-mir-1260b ; hsa-mir-4311 ; hsa-mir-8068 ; hsa-mir-412-3p ; hsa-mir-6844 ; hsa-mir-4709-5p ; hsa-mir-2115-3p ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-129-2/Upstream/74083; hsa-let-7a-2/Downstream/1474995;
Nearest TSS
ENST00000527297/Upstream/10686; ENST00000541372/Downstream/3960;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/10449, chr11-CpG: 78/Downstream/13911
Nearest cancer related gene
SLC3A2(OG, No orient, 0)
Upstream sequence
ttctgtacttgaggatactttatcagatagatttttggaacagggagattgaataaaaacttaaacttgctcatcctttttacaagtcaatatagtattg
Downstream sequence
cattacctccatgaatgctgTGGTTCTACCTTTTGGGGCAGATGTCAGTTAAAATTCAGACTGTCACATTCCACCGTATCTTTTGGTTTCTGGAAAAAAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate