Basic Information
VIS ID
TVIS44029872
Fusion event
HTLV-1-CDH13 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q23.3
Reference genome
NCBI36/hg18
Start
81705245/83114139 (Hg38)
End
81705245/83114139 (Hg38)
Orient
-
Location type
Intronic
Target gene
CDH13
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-181a-5p ; hsa-mir-4464 ; hsa-mir-4307 ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-31-3p ; hsa-mir-367-5p ; hsa-mir-1266-3p
Nearest miRNA
hsa-mir-1225/Upstream/425120; hsa-mir-11401/Downstream/394207;
Nearest TSS
ENST00000527434/Upstream/123841; ENST00000562307/Downstream/283848;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/485931, chr16-CpG: 67/Downstream/693668
Nearest cancer related gene
CDH13(TSG, No orient, 0)
Upstream sequence
CCCCTGATGAAAACTGTTACTTCTGTTCTCCACTCCCTTATTTGGGCAAAGCAGTTTATTTTCTACCCGAAGCATATCTACTAATAGAAATGACTGAGAT
Downstream sequence
ATTCATTACGTTAGGAATGTAATGTAATGATTCTTAGATGGTGATTCAGATGATTAGTTATTGGACCTTCGATGCATTTTTTATTTTAATTTTGAGATTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate