Basic Information
VIS ID
TVIS44029888
Fusion event
HTLV-1-RNF150 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
NCBI36/hg18
Start
142252219/141111615 (Hg38)
End
142252219/141111615 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4C
Target gene
RNF150
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-548v ; hsa-mir-548au-3p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-3149 ; hsa-mir-935 ; hsa-mir-5003-3p ; hsa-mir-6844 ; hsa-mir-4446-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-627-3p ; hsa-mir-7113-3p ; hsa-mir-6747-3p ; hsa-mir-6752-3p ; hsa-mir-330-3p
Nearest miRNA
hsa-mir-12113/Upstream/15604308; hsa-mir-1305/Downstream/2231845;
Nearest TSS
ENST00000502981/Upstream/114579; ENST00000514826/Downstream/21227;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/354599, chr4-CpG: 117/Downstream/20558
Upstream sequence
GGAGATCCACACTTGTGTTCAGAGGAAAAAAGGAATACTAAAGCTTTCTAATAAGAATCTTACAAGTGAAAGTACTAGGATTTATGTTAAAATCGCAACA
Downstream sequence
AAAGGGAACACTAAAAATAGACAAACGAATTCCTGAGCATGAGGAACCACAAATGCAATTAAAGAAAATGTTATTTAAAATCAAGGCTGTAGCAGTTTAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate