Basic Information
VIS ID
TVIS44029916
Fusion event
HTLV-1-SOBP integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
NCBI36/hg18
Start
108083151/107655254 (Hg38)
End
108083151/107655254 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6F
Target gene
SOBP
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-324-5p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-302f ; hsa-mir-5187-3p ; hsa-mir-8081 ; hsa-mir-432-5p ; hsa-mir-487b-3p ; hsa-mir-513b-5p ; hsa-mir-4424 ; hsa-mir-15b-3p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-6757-3p ; hsa-mir-7849-3p ; hsa-mir-599 ; hsa-mir-584-5p ; hsa-mir-2052 ; hsa-mir-144-5p ; hsa-mir-6814-5p ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-4733-5p ; hsa-mir-8076 ; hsa-mir-3123
Nearest miRNA
hsa-mir-10398/Upstream/871034; hsa-mir-1202/Downstream/11413793;
Nearest TSS
ENST00000381078/Upstream/20264; ENST00000606070/Downstream/76849;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/19765, chr6-CpG: 32/Downstream/192938
Upstream sequence
CAAGGACAAAACAGAACCAGCTCCAGACTCTGGAACTTCCTGCCATGATCACTTTCTAAAAATCCAAACTTATTTCCTCCCCACTCTGTTGGATTTCATA
Downstream sequence
CCTTCCATACCAATAAATATCAGAAAAGTGAAGCCCAAGCTTGGTTCTTCATTTTCATCGATTCCAGAGTCTTTTCCTGTGTCACCAACAAGGGGGCTGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate