Basic Information
VIS ID
TVIS44029917
Fusion event
HTLV-1-FAM189A2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q21.12
Reference genome
NCBI36/hg18
Start
71152167/69347431 (Hg38)
End
71152167/69347431 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM189A2
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-101-2/Upstream/28113596; hsa-let-7a-1/Downstream/1462544;
Nearest TSS
ENST00000422679/Upstream/18106; ENST00000645123/Downstream/23835;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/22044, chr9-CpG: 43/Downstream/64556
Upstream sequence
CCAAGTCCCAACATAACAGGCAGATGAACTCTCCCTGCCCGTTACCTTCCCTACCAACATGGCTGTGGCCTTCCCCACACCCCCTTCTATCAAACCCAAC
Downstream sequence
TGTGTTGTAGGGGGAGCAGTAGACCCACACGAAAAAAGGGAAACAGAGCAGATTGAGGCCATTCCCTTGCCTTCCCACGGCAGGCTTGCTCCCTGCCTAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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