Basic Information
VIS ID
TVIS44029921
Fusion event
HTLV-1-NOVA1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
NCBI36/hg18
Start
26022739/26483693 (Hg38)
End
26022739/26483693 (Hg38)
Orient
-
Location type
Intronic
Target gene
NOVA1
miRNAs that regulate target gene
hsa-mir-338-3p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-339-5p ; hsa-mir-146b-5p
Nearest miRNA
hsa-mir-208a/Upstream/2340128; hsa-mir-1185-1/Downstream/424949;
Nearest TSS
ENST00000550708/Upstream/340388; ENST00000547786/Downstream/111768;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/278421, chr14-CpG: 203/Downstream/2281990
Upstream sequence
caaacattatatgcttcttgatgtgatgtaataaaaaacacacagaaccaattatgatgtacctaaaagtagttgaacctaaatctaatcaAACATTTAG
Downstream sequence
CACTATAGATTAATACTGAAAACAGAACAATAAACGATACCATAAGGAAGCAAAGACACAAAAATAGTTTATAAGACAACTGATGCAGCTTCGTCAataa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate